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Its functions extend far beyond mere detoxification

NADPH oxidases (NOX) are another source of cellular ROS

Nat Neurosci 4:1169-1171

Here, we reviewed the omics studies related to ASD and the signaling pathways, in particular the convergent signaling pathways (Table S1) which associated with synaptic dysfunction, glutamatergic and GABAergic synapse imbalance, and postsynaptic density (PSD), as well as important physiological and metabolic abnormalities